Discussion: Environmental studies

Discussion: Environmental Factors

DR. WRIGHT: As a follow-up to my formal presentation, I would like to point out that the pathologists are quite aware of problems in diagnosing experimentally induced emphysema in an animal model. It would be nice to be able to perform the classical experiment, as exemplified in Pasteur's historical study of immunity to an-thrax in sheep, one in which a direct cause and effect can be demonstrat...

Discussion: Animal Studies

Cutaneous lesions that develop in the rabbit following inoculation of tick homogenates infected with Lyme disease spirochetes closely mimic erythema chronicum migrans (ECM) in humans. Dr. Kornblatt was able to induce ECM-like lesions in rabbits at the site of inoculation within a short period of time, but Dr. Burgdorfer observed the development of skin lesions in remote sites up to 12 weeks aft...

Discussion: Epidemiologic Studies

What is the distribution and population density of ticks transmitting the Lyme spirochete? Data on tick distribution are scarce. Ixodes dammini appears to be limited to sea-level ecosystems, whereas L pacificus populations are adequate up to 7,000 feet elevation. Three cases of Lyme disease had their exposure above 5,000 feet in the Sierras of northern California. The nymphal tick is very small...

Discussion Summary: Environmental Health—An Overview*

Review, discussion, and summary of epidemiological studies.

This paper reviews and summarizes the epidemiological studies presented at the Symposium on the Health Effects of Acid Aerosols. Two studies of acute episodes examined different indicators of respiratory morbidity before, during, and after the January 1985 air pollution event in western Europe. In the U.K. no increase in respiratory morbidity, as reported by a group of general practitioners, wa...